My research focuses on developing multiscale computational and experimental tools to advance our knowledge of cardiac biomechanics, remodeling, and electrophysiology, employing our models to design clinical therapies, and training a new, diverse generation of biomedical engineers.
Digital radiography, application of digital subtraction angiography to cardiac imaging, coronary artery flow measurement, digital image processing
Adult stem cell therapy and molecular diagnostics
Microfabrication and fiber-optic based biomedical imaging systems development
Cellular and tissue biomechanics, cellular mechanotransduction, tissue function, vascular mechanobiology
To improve cardiovascular health through the integration of mechanical engineering, vascular biology and imaging tools, to advance knowledge in these fields, and to educate the next generation of leaders in cardiovascular engineering and science.
Stem cell and tissue engineering, regenerative biology, cell reprogramming, epigenomics, mechanobiology
Applying multiscale computational modeling and tissue engineering to stem cell-derived cardiomyocytes (heart muscle cells), cardiac morphogenesis (development of structure), and cardiac function.
Endothelial cells as initiators and targets of immune responses and genes regulating endothelial cell tube formation/angiogenesis
Cell and tissue engineering, biomaterials, microfabricated technologies, mechanotransduction